Introducing the TranQoL for Use in Clinical Research

Dr. Robert Klaassen

TranQoL Instrument Author; Pediatric Hematologist and Oncologist, Clinical Investigator - CHEO Research Institute; Associate Professor, Faculty of Medicine/ Department of Pediatrics - University of Ottawa


What you will learn

  • Brief review of Thalassemia

  • Brief review of QOL

  • Development of the TranQol

  • Validation of the TranQol

  • Current translations

  • Access to TranQol


About Thalassemia

Thalassemia is an inherited blood disorder occuring from a defective globin gene synthesis which results in unbalanced chain synthesis. The unpaired chains are insoluble and adhere to the cytoskeleton leading to early cell death (ineffective erythropoiesis) or shortened red cell life span.

Thalassemia disease states are either:

  • Transfusion-Dependent
  • Non-Transfusion Dependent